Monitoring of Blood Concentration and Clinical Efficacy of Vancomycin in the Treatment of Patients with Critically Ill Infections

We attempt to discuss the clinical efficacy and safety of vancomycin in different blood concentrations patients with critically ill infections. collected 50 who received treatment from infectious diseases department our hospital June 2017 2021. Monitored trough concentration selected after reaching steady state. divided into three groups according minimum value i.e. <10 mg/l (n=16), 10 mg/l~15 (n=18) >15 compare effective rate adverse reactions among patients. 16 cases, 18 cases were enrolled <10, 10-15, cure rates 68.8 %, 66.7 % respectively. The differences had no statistical significance (p=0.983); overall was (9/50) group (43.8 7/16), especially it is acute renal dysfunction, which statistically other two (p=0.025). high infection does not increase its efficacy, but will provide a basis for providing best dose practice.